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In recent years, it has become clear that hypoxia-inducing factor (HIF) plays an important role in retinal diseases that cause blindness. 6 types of fish with HIF inhibitory activity have been screened out from the fish extracts in Shizuoka prefecture that have been collected and extracted at the Shizuoka Prefectural Fisheries and Marine Technology Research Institute. This year, from the obtained fish extracts, active substances were fractionated, purified, and structurally determined at the Fuculty of Agriculture, Shizuoka University. Then, we performed in vitro experiments and identified some of the active components at Laboratory of Photobiology, Keio University School of Medicine.
Shizuoka prefecture
October, 2019 - present
Seeds creation research work centered on marine biotechnology
Shizuoka Prefectural Research Institute of fishery and Marine
Fuculty of Agriculture, Shizuoka University
Shinanomachi
Toshihide Kurihara, MD/PhD
kurihara@z8.keio.jp
Exploring for hypoxia response regulative components derived from fishes caught in Shizuoka prefecture and disease control
October, 2019 - present
Exploring for hypoxia response regulative components derived from fishes caught in Shizuoka prefecture and disease control
October, 2019 - present
Exploring for hypoxia response regulative components derived from fishes caught in Shizuoka prefecture and disease control
October, 2019 - present