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In recent years, it has become clear that hypoxia-inducing factor (HIF) plays an important role in retinal diseases that cause blindness. 6 types of fish with HIF inhibitory activity have been screened out from the fish extracts in Shizuoka prefecture that have been collected and extracted at the Shizuoka Prefectural Fisheries and Marine Technology Research Institute. This year, from the obtained fish extracts, active substances have being fractionated, purified, and structurally determined at the Institute of Green Science and Technology, Shizuoka University. Then, we are verifying the physiological activity in vitro and in vivo at Laboratory of Photobiology, Keio University School of Medicine.
Shizuoka prefecture
October, 2019 - present
Seeds creation research work centered on marine biotechnology
Shizuoka Prefectural Research Institute of fishery and Marine
Shizuoka University Research Institute of Green Science and Technology
Shinanomachi
Toshihide Kurihara, MD/PhD
kurihara@z8.keio.jp
Exploring for hypoxia response regulative components derived from fishes caught in Shizuoka prefecture and disease control
October, 2019 - present
Exploring for hypoxia response regulative components derived from fishes caught in Shizuoka prefecture and disease control
October, 2019 - present
Exploring for hypoxia response regulative components derived from fishes caught in Shizuoka prefecture and disease control
October, 2019 - present