Organizational System for Community and Regional Affairs Organizational System for Community and Regional

SDGs

Exploring for hypoxia response regulative components derived from fishes caught in Shizuoka prefecture and disease control

In recent years, it has become clear that hypoxia-inducing factor (HIF) plays an important role in retinal diseases that cause blindness. 6 types of fish with HIF inhibitory activity have been screened out from the fish extracts in Shizuoka prefecture that have been collected and extracted at the Shizuoka Prefectural Fisheries and Marine Technology Research Institute. This year, from the obtained fish extracts, active substances have being fractionated, purified, and structurally determined at the Institute of Green Science and Technology, Shizuoka University. Then, we are verifying the physiological activity in vitro and in vivo at Laboratory of Photobiology, Keio University School of Medicine.

Applicable regions

Shizuoka prefecture

Implementation period

October, 2019 - present

Community and Regional Affairs category

• Regional collaboration as research targets and implementation sites/research that aims to popularize region-specific issues

Related websites

Marine Open Innovation (MaOI) project

Press release regarding the collaborative study

Related agreements, etc.

Seeds creation research work centered on marine biotechnology

Cooperating institutions, etc.

Shizuoka Prefectural Research Institute of fishery and Marine
Shizuoka University Research Institute of Green Science and Technology

Campus

Shinanomachi

Person in charge

Toshihide Kurihara, MD/PhD

Inquiries

kurihara@z8.keio.jp